Zogenix, Inc. (NASDAQ:ZGNX) has reported positive results for its drug – Fintepla during the clinical trial to treat Lennox-Gastaut syndrome. However, the drug failed to produce impressive results when compared to a placebo. Fintepla could reduce seizures by 26.5% when compared to a reduction of 7.8% in patients, who are administered a placebo.
Epidiolex produces impressive results
GW Pharmaceutical’s Epidiolex, cannabidiol derived from cannabis, helped to reduce seizures by 44% and 42% during two clinical trials. It has got the nod of the US FDA to cure patients suffering from Lennox-Gastaut syndrome. According to the results obtained from clinical trials, Epidiolux provides better results when compared to Fintepla.
Shares of GW Pharmaceuticals inches up
The shares of GW Pharmaceuticals have surged by 7% on February 7, 2020, on the news of its rival failed to produce not so impressive results. Zogenix shares have declined by 37% on February 7, 2020, because it failed to beat the results of Epidiolex in curing Lennox-Gastaut syndrome.
Fintepla offers better results in curing Dravet Syndrome
Zogenix has tested Fintepla in treating childhood epilepsy – Dravet Syndrome. A higher dosage of the drug helped to reduce monthly convulsion seizures by over 60% in two clinical trials. It submitted the results to the US FDA and expects to receive approval on March 25, 2020.
Mark Goodman, an analyst at SVB Leerink, said expectations of thee investors on the drug’s effectiveness in reducing the seizures in patients suffering from Lennox-Gastaut syndrome are higher. However, the drug failed to meet their expectations. He expects that peak sales of the drug in the US would decline to $700 million from the previous projection of $1 billion.
Mark said seizures reductions through the administration of Fintepla are in line with the results of other approved drugs that include Epidiolux of GW Pharmaceuticals. But, its results are less robust when compared to Epidiolux.
Zogenix has reported revenues of $0.63 million in Q3 2019. It has missed the Zacks Consensus expectations by 42.73%.
Zogenix acquired Modis Therapeutics, a privately held company, in a deal valued at $250 million. Modis Therapeutics focuses on the development of drugs for the treatment of rare genetic diseases.